Frontline Plus for Cats . (S)-methoprene is an insect growth regulator (IGR) of the class of compounds known as juvenile hormone analogues that inhibit the development of immature stages of insects. Treatment and prevention of flea infestations and biting lice and control of flea allergy dermatitis on cats. In addition, the oil must come from an Eastern Red Cedar (Juniperus virginiana), as the cedar oil from White cedar (Melia azedarach) is toxic to cats. (S)-methoprene alone is well tolerated by dogs and cats, with a low toxicity and high safety margin. Uses of Fipronil and Methoprene for Dogs and Cats Fipronil and methoprene is used in the control and treatment of all stages of flea infestations and tick infestations in dogs and cats. It does not kill fleas but disrupts their life cycle, preventing early stages from developing into adults. S-methoprene is a growth regulator that acts as an important juvenile hormone in insects to prevent pupa and larva from developing into adults. JavaScript seems to be disabled in your browser. Combined ingredient products are supplied as topical solutions. Prevents the development of flea eggs, larvae and pupae produced by adult fleas acquired for six weeks after treatment. It can be used on kittens from 8 weeks of age and is safe to use on breeding, pregnant or lactating animals. However, if you are a dog or cat owner, you might be interested to learn that S-Methoprene is in fact one of the active ingredients in the popular flea and tick control pet medications Frontline Plus for dogs and Frontline Plus for cats. In addition, the insect growth inhibitor s-methoprene kills flea eggs and larvae and thus disrupts the life cycle of ticks and fleas. caterpillar) to the adult phase (i.e. It has also been used to treat Cheyletiellosis(Walking Dandruff Mite)in dogs and cats. Frontline Plus has a rapid onset of action and kills re-infestations with newly acquired adult fleas for at least 1 month, and also prevents the development of flea eggs, larvae and pupae produced by any adult fleas acquired for up to 3 months after treatment. Administration to kittens under 8 weeks of age; administration to rabbits. Our Mission is to help make treating your pet's diseases easier and more affordable. Fast Action and Effective - Fleas killed within 24 hours of application on cats - For tick control on cats, use FRONTLINE SPRAY. It works by not allowing the target insect from reaching the point of maturity, which will halt the potential that it can reproduce. Socha R et al (1990) Comments on safety of methoprene. However, as noted in our Buyer’s Guide, pyrethrins are “extremely toxic to cats.” Pyrethrins are also toxic to humans, and therefore please follow the label instructions carefully. Methoprene Cats. Boehringer Ingelheim Animal Health Australia Pty Ltd, Waterfast or Water Resistant for a month after 48 hours of application. It works rapidly and is for use on dogs 12 weeks of age and older. Absolutely! This prevents the insects from reproducing. Fipronil, methoprene, and etofenprox is a combination flea and tick control product that kills existing fleas and ticks to eliminate and prevent infestations for one month following application. The veterinary medicinal product is exclusively indicated when all three groups are targeted at the same time.EctoparasitesTreatment and prevention of infestations by fleas (Ctenocephalides felis). This application rate is ten times the suggested rates. Frontline Plus is made of two major ingredients – fipronil and (S)-methoprene. The second ingredient (S)-methoprene acts as an insect growth regulator and destroys the immature life stages of fleas. Acute Toxicity and Tolerance of Etofenprox. Thus, as you can see, both the Frontline products have the exact same Fipronil content, but the difference lies in the percentage of the ingredient S-Methoprene. Australia's first and only dedicated animal pharmacy, A convenient way to purchase all your pet’s medicines, The most affordable medications for your pet in all of Australia, Fast turnaround so receive your orders promptly, Registered NSW pharmacy providing APVMA approved veterinary medicines, Customer Service: 8am - 6pm | Mon - Fri 8am - 4pm | Saturday, The Animal Pharmacy Shop 2, The Village 3 Julius Avenue North Ryde NSW 2113 Australia, Only registered users can write reviews. Topical treatment that quickly and effectively kills fleas, flea eggs, deer ticks, and repels mosquitos. (S)-methoprene acts by contact. It does not kill fleas but disrupts their life cycle, preventing early stages from developing into adults. Extinguish with alcohol-resistant foam, carbon dioxide, dry powder or water fog. The activity of the compound as a juvenile hormone is restricted to the S enantiomer. Pet Bucket Ltd is a UK registered company | Company no: 08345021 | BTC Bessemer Drive Stevenage | SG1 2DX UK, Duoflect Topical Solution for Dogs and Cats (with Fipronil). For external application. While Frontline Plus for dogs has 9.8% of Fipronil content and 8.8% of S-methoprene content, Frontline Plus for cats has 9.8% of Fipronil, but 11.8% of S-Methoprene. Methoprene is commonly found in flea treatments for dogs and cats, in cattle feed to control flies, and in mosquito control products. Methoprene is an insect growth regulator. The Animal Pharmacy has the largest range and the cheapest prescription animal medicines in Australia. This information is provided for general reference only and is not intended to replace the packaging label or veterinary advice. JAVMA 206(8) 1137-1143. Long Lasting - Kills and controls fleas for up to a month. The Animal Pharmacy is an Australian supplier of prescription and non-prescription veterinary medicines. (S)-methoprene is a larvicide used to control fleas in dogs and cats. The first ingredient – Fipronil acts as adulticide and removes adult fleas and ticks. Usually, the onset of action is 30 minutes, and its effect lasts for 48 hours upon which most adult fleas would have died. Harvey R G et al (1997) Prospective study comparing fipronil with dichlorvos/fenitrothion and methoprene/pyrethrins in control of flea bite hypersensitivity in cats. All Rights Reserved. NSW Pharmacy Registration Number: PC0030058. moth). Use fire-extinguishing media suitable for the surrounding fire. Methoprene is the common name for isopropyl-(2E,4E,7R,S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate.It is a racemic mixture of two enantiomers (R and S in a ratio of 1:1). LD50 acute, rats, dermal, >2000 mg/kg LD50 acute, dogs, dermal, >5000 mg/kg Etofenprox is less irritant than most pyrethroid esters (e.g. Effective formula stops the flea life cycle and prevents re-infestation for up to 30 days. Therefore methoprene is like “birth control” for pests. Formulated for cats and kittens over 5 pounds that are 12 weeks of age or older. Our pharmacy registration means that we can send medicines to all States and Territories of Australia. An insect growth regulator, (S)-methoprene [90 g/L (9%) for dogs or 120 g/L (12%) for cats], has also been included with several of the products containing fipronil (e.g. Fipronil, methoprene, and cyphenothrin, when used properly, can significantly reduce the risk of numerous potentially serious diseases and conditions, including Lyme di… For cats with, or at risk from mixed infestations by cestodes, nematodes and ectoparasites. However, if you suspect your pet has had an overdose of any medication, please contact your veterinarian immediately. For external use only. Please. As such (S)-methoprene is not used as a single ingredient product, but combined with adulticides … The study was conducted in order to evaluate the effect of a fipronil/(S)-methoprene formulation against fleas on naturally infested cats. Includes three easy to use monthly applications. The product works rapidly and is for use on cats and kittens 12 weeks of age and older. Unsuitable extinguishing media Do not use water jet as an extinguisher, as this will spread the fire. To order a prescription medicine, make sure to follow these simple three steps. Rapid and long-acting treatment and prevention of flea infestations on cats and persistent effect on environmental stages of fleas. IGRs such as methoprene are used to disrupt and impede the life cycle of insects in the egg and larvae stage of development. By acting like an insect hormone, it interferes with insect growth and development. Is cedarwood safe for cats? Methoprene is a hormone that comes in two forms: r-methoprene and s-methoprene. Methoprene applied at a concentration of 0.2 ppm did not significantly affect the locomotor activities of mosquitofish or goldfish. (S)-methoprene is a larvicide used to control fleas in dogsand cats. It can prevent normal molting, egg-laying, egg-hatching, and development from the immature phase (i.e. >2000 mg/kg. The idea behind IGR use is that if a given insect cannot reach adulthood, it cannot reproduce. The study was conducted in order to evaluate the effect of a fipronil/(S)-methoprene formulation against fleas on naturally infested cats. In a normal life cycle, an insect goes from egg to larva to pupa and eventually to adult. The Best Essential Oils for Cats Cedarwood . According to the EPA, the chemical methoprene is considered an insect growth regulator. Smith C A (1995) Searching for safe methods of flea control. (S)-Methoprene is an insect growth regulator, or more precisely, a juvenile hormone mimic. Avoid contact with eyes and skin. It is also used for the treatment and control of chewing lice in dogs, puppies, kittens and cats. In terms of region, the methoprene market can be categorized into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. It is used as an insecticide because it interferes with the normal maturation process. The sesame oil helps the product to spread over the cat’s skin and acts as a coat conditioner as well. Fipronil, methoprene, and cyphenothrin is a combination flea and tick control product that kills existing fleas and ticks and helps prevent new infestations for a full month following application. Poisoning by (S)-methoprene alone is rare due to its low toxicity. Fast Action and Effective - Fleas killed within 24 hours of application on cats - For tick control on cats, use FRONTLINE SPRAY. If product enters eyes, wash it out immediately with water. Frontline Plus (fipronil Plus (s)-methoprene) For Cats - Parasiticides - Cat - Breeding | Cat - Female (queen) | Cat - Over 8 Weeks Of Age | Castrate | Cat - Queen - Catbiting Louse | Flea - Ctenocephalides Spp. For best results, brush your cat's fur 24 hours after application to distribute the treatment and the coat conditioning sesame oil. The maximum concentrations were reached 24 h after dosing in the majority of the animals (six of eight cats). For the best experience on our site, be sure to turn on Javascript in your browser. Ask your vet to kindly write a prescription. Side effects experienced by dogs and cats after treatment with products containing (S)-methoprene can generally be attributed to the other active or inert ingredients. For the best experience on our site, be sure to turn on Javascript in your browser. (S)-methoprene is not available as a single ingredient product. The manufacturer says this is an “EPA-regulated spray” that may be applied directly to your cats, cat bedding, carpets, and floor gaps. s-Methoprene TG Extinguishing media Suitable extinguishing media The product is not flammable. Methoprene-membrane interaction and perturbation of cell bioenergetics may underlie the mechanism of toxicity of this compound in non-target organisms. LD50 acute, rats, p.o. Unless you are a vet or have studied chemistry, it is unlikely that the name S-Methoprene means much to you. Fipronil aids in the control of sarcoptic mange infestations in dogs. The average terminal half-life was 114 h due to slow absorption (‘flip-flop’ kinetics). What is S-Methoprene? This chemical is extremely effective when used for several different types of insects and pests, which include: